2 Chronicles 26:19-21

But Uzziah, censer in hand, was already in the middle of doing it and angrily rebuffed the priests. He lost his temper; angry words were exchanged—and then, even as they quarreled, a skin disease appeared on his forehead. As soon as they saw it, the chief priest Azariah and the other priests got him out of there as fast as they could. He hurried out—he knew that GOD then and there had given him the disease. Uzziah had his skin disease for the rest of his life and had to live in quarantine; he was not permitted to set foot in The Temple of GOD. His son Jotham, who managed the royal palace, took over the government of the country.