Revelation 16:2-3

So the first angel went and poured out his bowl on the earth; and loathsome and malignant sores came on the people who had the mark of the beast and who worshiped his image. [Ex 9:10, 11; Deut 28:35] The second angel poured out his bowl into the sea, and it turned into blood like that of a corpse [foul and disgusting]; and every living thing in the sea died.