Acts 16:4-9

They went out together as missionaries, traveling to different cities where they preached and informed the churches of the decrees of the apostolic council of Jerusalem for the non-Jewish converts to observe. All the churches were growing daily and were encouraged and strengthened in their faith. The Holy Spirit had forbidden Paul and his partners to preach the word in the southwestern provinces of Turkey, so they ministered throughout the region of central and west-central Turkey. When they got as far west as the borders of Mysia, they repeatedly attempted to go north into the province of Bithynia, but again the Spirit of Jesus would not allow them to enter. So instead they went right on through the province of Mysia to the seaport of Troas. While staying there Paul experienced a supernatural, ecstatic vision during the night. A man from Macedonia appeared before him, pleading with him, “You must come across the sea to Macedonia and help us!”